View this post on Instagram A post shared by imedscholar (@imedscholar_official) Oedema means an abnormal or excessive accumulation of fluid in the tissue spaces of the body. PITTING EDEMA: Subcutaneous edema leads to Pitting edema i.e. it is recognized by digital pressure. eg-Congestion, Hypoalbuminemia NON-PITTING EDEMA: seen in Filariasis (Elephantiasis) Myxoedema Scleredema, Scleroderma …
Pathology open blog
Download the PDF for Shock by clicking the link below – Notes made by Nikita Balani We hope it helps you!
Download the PDF for Embolism by clicking the link below – Notes made by Nikita Balani We hope it helps you!
Leprosy/ Hansen’s disease ETIOLOGY Leprosy is a chronic infectious disease caused by M.Leprae- an acid fast bacilli. The route of transmission is unclear but is thought to be via nasal droplet infection and contact transmission. The organism prefers cooler temperature (body surface temperature is less than core body temperature) and hence it mainly involves skin …
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Mostly the alternate pathway of complement activation is involved. (Evidence – decreased serum C3 level and normal C1,C2 and C4). The deposits of C3 (granular pattern) is seen in glomeruli. C3NeF (Circulating anti complementary nephritic factor) is an Autoantibody (Ig) – binds to C3 convertase and stabilise it leading to its persistent activation. EPITHELIAL INJURY …
Let’s first understand what it means. ACUTE– transient in nature (rarely leads to renal failure) PROLIFERATIVE– proliferation of endothelial and mesangial cells POST– 1-4 weeks after INFECTIOUS– Occurring because of infections like staphy, strept. GLOMERULONEPHRITIS– Inflammation of glomerulus. PATHOGENESIS The basic mechanism which underlies this disease is SUBEPITHELIAL immune complex deposition. So, just let’s go …