Open blog

-BY MANSI NAHAR

Leprosy/ Hansen’s disease ETIOLOGY Leprosy is a chronic infectious disease caused by M.Leprae- an acid fast bacilli. The route of transmission is unclear but is thought to be via nasal droplet infection and contact transmission. The organism prefers cooler temperature (body surface temperature is less than core body temperature) and hence it mainly involves skin …

Leprosy/ Hansen’s disease Read More »

Pathophysiology Pulmonary edema is caused because of transudation of fluid, RBCs and macromolecules from the pulmonary capillaries into the interstitium and then into the alveoli an bronchioles. This takes place because of the following factors: 1.Increased pulmonary capillary pressure 2.Widening of the intercellular junctions between the pulmonary capillary endothelium 3.Disruption of the intercellular junctions Causes …

Pulmonary oedema Read More »

X-linked dominant disorders 1.Familial hypophosphatemic rickets2.Urea cycle defect due to deficiency of ornithine transcarbamylase3.Incontinentia pigmenti4.Rette’s syndrome   X-linked recessive disorders 1.Duchenne muscular dystrophy2.G6PD deficiency3.Hemophilia A and B4.Color blindness5.Lesch Nyhan syndrome6.FABRY’s disease7.Wiskott Aldrich syndrome8.Chronic granulomatous disease   Other similar posts: Autosomal dominant disorders Autosomal recessive disorders  

Autosomal recessive disorders include most of the metabolic problems. Cystic fibrosis Wilson’s disease Gaucher’s disease Alpha -1-antitrypsin deficiency Hemochromatosis Neiman-Picks disease Hurler’s disease Tay-Sachs disease Fredrick’s ataxia   Other similar posts: X-linked dominant and recessive disorders Autosomal dominant disorders

We can remember the Autosomal dominant disorders by the mnemonic- DOMINANT VH3 D– Dystrophia myotonica O– Osteogenesis imperfecta M– Marfan’s syndrome I– Intermittent porphyria N– Noonan’s syndrome A– Achondroplasia, Adult polycystic kidney disease N– Neurofibromatosis T– Tuberous sclerosis V– Von Willebrand’s disease H– Hypercholesterolemia H– Huntington’s chorea H– Hereditary spherocytosis -Mrunali Gondane Other similar posts: …

Autosomal dominant disorders Read More »

Anaphylactic shock Adrenaline 0.5 ml sc / im Hydrocortisone 200 mg iv Diphenhydramine 25-50 iv/im Hypoglycemia Oral glucose Fruit juice 50 ml of 50% iv Glucose Glucagon Acute Myocardial infarction •Attach a Cardiac monitor •Administer Oxygen if oxygen saturation is <94% •Establish iv access •Nitroglycerin 0.5 mg sublingual •Morphine 5 mg iv with an Antiemetic …

Must know drugs for medical emergencies Read More »

Status epilepticus is sustained epileptic activity with1. two fits without recovery of consciousness in betweenOR2.single fit of >30 mins with or without loss of consciousness Treatment aims at controlling seizures within 1 hour of admission. STEP A (first 20 mins) Maintain ABC (airway, breathing, circulation) measure blood sugar take a brief history Administer Diazepam (10 …

Status epilepticus Read More »