Hepatic encephalopathy is due to rise in ammonia levels in blood Etiopathogenesis : Increased ammonia level in blood (Most important) Increase in short chain fatty acids Rise in methionine level Rise in false neurotransmitters like octopamine Increased conversion of tryptophan to inhibitory neurotransmitter serotonin Increased sensitivity of CNS neurones to GABA (inhibitory neurotransmitter) Increased conversion …
