Click on the link to download pdf Fatty Liver —Mansi Nahar
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Features of cholesterol synthesis Acetate of acetyl CoA provides all carbons Reducing equivalents are supplied by NADPH and ATP provides energy For producing 1 mole of cholesterol, 18 moles of acetyl CoA, 36 moles of ATP and 16 moles of NADPH are required. There are 5 stages in synthesis of cholesterol 1. Synthesis of HMG …
WHAT ARE ISOTOPES Elements with same atomic number (SAN) but different atomic weights (DAW). TYPES OF ISOTOPES There are two types of isotopes: Stable Isotopes Naturally occurring Do not emit radiations Identified and quantitated by mass spectrometry or nuclear magnetic resonance. Sometimes used in biochemical investigations. Unstable or Radioactive Isotopes (IMP SAQ) Nucleus unstable …
Central Dogma Of Protein Synthesis: (By Crick) DNA ↓ m-RNA ↓ Protein Genetic Code: Dictionary of nucleotide base combinations which determine sequence of amino acids in proteins. Codon: A sequence of 3 nucleotide bases on m-RNA which codes for a single amino acid. E.g. AUG codes for methionine (Number of Codons= 4 …
Responsible for 80% of all cancers Organic: Dimethyl benzanthracene, Benzo(a)pyrene Inorganic: Arsenic, Cadmium MECHANISM OF ACTION Direct acting Indirectly acting: Procarcinogen → Ultimate carcinogen (via CYP 450 enzymes) Adduct formation with Purines, Pyrimidines ⇓ Breakage of phosphodiester bonds …
First, let us learn what is metabolism of xenobiotics.. Detoxification – The series of biochemical reactions occurring in the body to convert foreign compounds to non-toxic and more easily excretable form. Xenobiotic is any foreign or strange substance to the body. Detoxification of this is called metabolism of xenobiotics. The metabolism of xenobiotics is …
Click on the link to download the pdf Glycogenolysis — Mansi Nahar
LIVER FUNCTION TESTS What is LFT? LFTs are used for mainly 2 reasons: To confirm clinical suspicion of potential liver injury or disease. To distinguish between hepatocellular injury (hepatic jaundice) and cholestasis (post hepatic or obstructive jaundice). Classification LFTs are classified according the functions of liver: Tests based on excretory function- Measurement of bile pigments, …