AAaaa HMP (Pentose) Pathway Is Difficult 😱, Go Forward and Study Liver’s Cholesterol !
A– Acetyl CoA
A– Acetoacetyl CoA
H– HMG CoA
M– Mevalonate
P– 5-Phosphomevalonate
P– 5-Pyrophosphomevalonate
P– 3-Phospho 5-pyrophosphomevalonate
I– Isopentenyl pyrophosphate
D– Dimethyl allyl pyrophosphate
G– Geranyl pyrophosphate
F– Farsenyl pyrophosphate
S– Squalene
L– Lanosterol
C– Cholesterol
A few other important points:
Cholesterol has 27 carbon atoms. Cholesterol synthesis takes place mainly in the liver. The enzymes for cholesterol synthesis are in the cytosol. The rate limiting enzyme is HMG CoA reductase.
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